Differences of Erythrocyte Index in Patients With Diabetes Mellitus Given The Criteria for Prediabetes And Diabetes at Kedungdoro Public Health Center Surabaya

Abstract

Diabetes Mellitus is a metabolic disease characterized by high blood glucose levels due to impaired insulin
secretion, decreased insulin action, or both. Diabetes mellitus is divided into prediabetes criteria, namely when
fasting blood sugar levels are 100-125 mg/dL and diabetes criteria when fasting blood sugar levels are 126 mg/dL.
Elevated blood sugar levels are associated with a deficiency of Erythropoietic Stimulating Factors (ESF) which
can affect the process of erythrocyte formation to have an impressive effect on the erythrocyte index (MCV, MCH,
and MCHC). This study aims to determine the difference in index of erythrocytes in patients with prediabetes and
diabetes in Puskesmas Kedungdoro Surabaya. This research was observational analytic with crosssection
conducted from January to April 2021 in 15 patients with prediabetes and 15 diabetic patients at the health center
Kedungdoro Surabaya using materials EDTA blood test. Complete blood counts were carried out at the Bakti
Analytical Clinical Laboratory using the ABX Micros 60 Hematology Analyzer.The results showed the average
MCV value of prediabetic patients was 86.80 m3 while in diabetic patients it was 82.00 m3
, the average MCH of
prediabetic patients was 29.48 pg and in diabetic patients is 27.25 pg, and the average MCHC of prediabetes is
33.94 g/dLwhile in diabetic patients it is 33.20 g/dL. So that further research is needed on risk factors that can
increase the value of the erythrocyte index in people with diabetes mellitus.